Scientists have a new tool to help them tease out the immune system's mysteries. Researchers cultured human B and T cells inside a microfluidic Organ Chip and coaxed them to form functional lymphoid follicles (LFs) -- structures that reside in lymph nodes and other parts of the human body and mediate immune responses. The LF Chip replicated human immune responses to both pathogens and a commercial influenza vaccine in vitro, offering significant improvement over existing preclinical models like cells in a dish and non-human primates.
from All Top News -- ScienceDaily https://ift.tt/wFhV6Su
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